Drugs may be given by different routes in order to exert systemic or local non- IM drug is administered, distribution may occur at various rates and to various absorption following IM injection, and distribution of drugs in muscular tissue. 1. extravascular routes. For oral dosing, such factors as surface area of the GI tract, stomach-emptying rate, GI mobility, and blood flow to the absorption site all 

15 Sep 2017 Absorption is the process by which the drug gets from its site of administration to Factors which influence drug absorption from various routes. For many IN medications the rates of absorption and plasma concentrations are Drugs that are delivered by other routes (IV, IM, SQ, nasal) do not enter the  Drugs may be given by different routes in order to exert systemic or local non- IM drug is administered, distribution may occur at various rates and to various absorption following IM injection, and distribution of drugs in muscular tissue. 1. extravascular routes. For oral dosing, such factors as surface area of the GI tract, stomach-emptying rate, GI mobility, and blood flow to the absorption site all  1 Nov 2014 Subcutaneous injection is an important route of administration for for decades for administration of drugs such as insulin, erythropoietin, and growth Other factors controlling the rate and the extent of absorption include the  21 Jun 2016 Some Characteristics of Common Routes of Drug Administrationa The rate of absorption of a drug administered as a tablet or other solid oral 

More information about the oral route of drug administration: Oral (p.o.) Ingestion a. Additional variables which may influence rate and extent of absorption by host or bacterial enzymes, dietary contents, and presence of other drugs. c.

Dr.Abdul latif Mahesar ROUTES OF ADMINISTRATION ▻Enteral (Alimentary) Due to slow rate of absorption adverse effects occurs less and slowly as compared to Drug interaction: one drug can affect the absorption of other drug e.g.,  Nasal drug absorption enhancers and to the oral route for drug absorption in The rate and extent of absorption as it is not applicable to all drugs. Start studying Routes of Medication Administration and Absorption Rates of Medications. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Produces a faster effect than oral administration, however the rate of absorption depends greatly on the site of injection and on local blood flow. The drug can be aqueous solutions or depot preparations (in a form of ester or salt). The absorption of the aqueous is fast and the depot form is slow.

The four processes involved when a drug is taken are absorption, distribution, metabolism and elimination or excretion (ADME). Pharmacokinetics is the way the body acts on the drug once it is administered. It is the measure of the rate (kinetics) of absorption, distribution, metabolism and excretion (ADME).

In addition, the rate of absorption can be manipulated by using different formulations of the drug (e.g., fast-acting versus slow-acting insulin preparations). This route is not appropriate for solutions that are irritating to tissue because these may produce necrosis and sloughing of the skin. My exam is next monday and my teacher is conveniently on vacation! I need some help with the fastest to slowest routes of administration!! I am getting confuseddifferent sources, different rankings! LOL Please rank these for me in order from fastest rate of absorption to the slowest: inhalatio --It can involve taking different drugs in sequence in order to move from one drug experience to another. One characteristic of the subcutaneous route of injection is its associated _____ and _____ absorption rate. Slow; constant The transdermal route of drug administration is an effective one for most drugs. Intramuscular (IM) Produces a faster effect than oral administration, however the rate of absorption depends greatly on the site of injection and on local blood flow. The drug can be aqueous solutions or depot preparations (in a form of ester or salt). The absorption of the aqueous is fast and the depot form is slow. The stomach has a relatively large epithelial surface, but its thick mucous layer and short transit time limit absorption. Because most absorption occurs in the small intestine, gastric emptying is often the rate-limiting step. Food, especially fatty food, slows gastric emptying (and rate of drug absorption), The speed of absorption varies with parenteral administration, but it is faster than oral administration, which is a nonparenteral route. Some of the disadvantages of using the parenteral route are that there is a slight risk of infection, tissue damage, pain and/or anxiety for some patients. Start studying Routes of Medication Administration and Absorption Rates of Medications. Learn vocabulary, terms, and more with flashcards, games, and other study tools.

20. First-pass Effect cont. Magnitude of first pass hepatic effect: Extraction ratio (ER) ER = CL liver / Q ; where Q is hepatic blood flow (usually about 90 L per hour. Systemic drug bioavailability (F) may be determined from the extent of absorption (f) and the extraction ratio (ER): F = f x

On the other hand, drug absorption via this route is incomplete and erratic, in part In addition, the rate of absorption can be manipulated by using different  Produces a faster effect than oral administration, however the rate of absorption depends greatly on the site of injection and on  Table 1: Pros and cons of different routes of drug administration. Route Unpredictable absorption due to degradation by stomach acid and enzymes. Rectal. To obtain a general effect, the drug is usually given by oral or parenteral route. The rate of resorption is fast and it is possible to inject aqueous or oily solutions. Mouth: the absorption of the drug by the oral mucous membrane allows a fast absorption There are various devices for cutaneous administration, from simple  

Start studying Routes of Medication Administration and Absorption Rates of Medications. Learn vocabulary, terms, and more with flashcards, games, and other study tools.

For many IN medications the rates of absorption and plasma concentrations are Drugs that are delivered by other routes (IV, IM, SQ, nasal) do not enter the  Drugs may be given by different routes in order to exert systemic or local non- IM drug is administered, distribution may occur at various rates and to various absorption following IM injection, and distribution of drugs in muscular tissue. 1. extravascular routes. For oral dosing, such factors as surface area of the GI tract, stomach-emptying rate, GI mobility, and blood flow to the absorption site all  1 Nov 2014 Subcutaneous injection is an important route of administration for for decades for administration of drugs such as insulin, erythropoietin, and growth Other factors controlling the rate and the extent of absorption include the 

21 Jun 2016 Some Characteristics of Common Routes of Drug Administrationa The rate of absorption of a drug administered as a tablet or other solid oral  More information about the oral route of drug administration: Oral (p.o.) Ingestion a. Additional variables which may influence rate and extent of absorption by host or bacterial enzymes, dietary contents, and presence of other drugs. c.